Wednesday, March 10, 2010

Abstract | Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation

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Abstract | Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation

This is a very easy-to-read abstract (even the medical jargon is explained) that suggests that if we have XMRV, we should think very hard before donating blood or organs. Of course, we often harbor other transmittable infections which also could endanger transplant patients, so we already know that we could harm someone. Even our partners.

I am a strong advocate for checking the little box on your license that allows your organs to be transplanted after death, so in the past ten years, I've found it very unfortunate that I won't be able to offer my organs for transplantation after my death because of all the various Herpes infections I have that would cause a severe infection to a transplant patient.  The reason that transplantation patients are vulnerable is because their immune systems have been lowered so their body doesn't reject the organ itself.

While the blood donation centers won't take blood from someone who says that they don't feel well. Consider this:  A relative needs blood and the family and friends are polled to ease the financial burden for the patient by donating their blood. Along with that, you suddenly find yourself feeling well enough to donate. What a dilemma! You want to help the patient.Rather than allow the donation center to go through all the necessary motions to take your blood, test it, and perhaps miss or overlook your
HHV-6 (from roseola),
Herpes Simplex  (#1 and 2 are no longer differentiated), (cause cold sores and canker sores)
Epstein-Barr  (HHV-4) (causes mononucleosis),
CMV cytomegalovirus (HHV-5) (possibly also from mononucleosis),
varicella-zoster (VZV) (HHV-3)(from chickenpox)
HHV-7 (posssibly also from roseola), and/or
HPV (human papillomavirus), when all you have to do is inform them of your particular infection(s). At most centers, you and the patient will be credited with your attempted donation but will be listed as declined by the center.

Of course, you can't tell them if you don't know what co-infections you have. Please, if you can afford it and you have Lyme Disease, CFS, FM, lupus or any disease that impacts your immune system, ask to be tested for your viral load. In other words, test for all the various Herpes, and all the other usual suspects found in these diseases like borreliosis, bartonella, mycoplasma, etc.

Just like Herpes and other STD's, I'm certain that in the months or short years to come, all questions concerning the transmitability of XMRV will be answered. The study concludes that in the meantime, one should be very cautious and  inform everyone who might come in contact with your blood.


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I thought that my "troubles" began in 1989 when I was rear-ended by a druggie going 60 miles an hour while I was stopped at a city red light. Two years later, Fibromyalgia was diagnosed. Since I had all the symptoms, it seemed like a valid diagnosis and I was grateful to finally be diagnosed with something! Subsequently, I spent many years immobilized with widespread pain secondary to only being treated with a series of SSRI's. In 1994 I had to retire early and lost my new husband who, like my former employer, just couldn't understand my sudden change in behavior and decrease in mental faculties. To be somewhat fair, those were the "Dark Ages" in Fibromyalgia treatment. I didn't know until 2001 that my "troubles" had started on a beautiful day in 1985 when walking on the Mohawk Trail in NY I was bitten by a microscopic tick and developed Lyme Disease that was misdiagnosed as psychiatric problems, FM then CFS for the next 15 years. If my story sounds like yours, please, PLEASE get tested for Lyme by a reputable laboratory and interpreted by what we call a LLMD (Lyme-literate MD).Both the lab and the MD are equally important to your quality of life.